Staff at the University of Edinburgh have overwhelmingly voted in favour of strike action in a dispute over plans to cut £140m from its budget.
The University and Colleges Union (UCU) said the institution had refused to rule out compulsory redundancies as part of the "unprecedented" cuts.
It comes a day after the university's most senior academic body passed a vote of no confidence in its leadership over the financial position.
The university's principal, Prof Sir Peter Mathieson, said failure to take cost-saving action would leave it in an "unsustainable situation".
UCU members voted 84% in favour of industrial action in a ballot launched last month, with a turnout of 60%.
Action short of a strike, which could include a marking and assessment boycott, was also favoured by 93% of members.